立福康唑；182760-06-1

英文名称：Ravuconazole
CAS号：182760-06-1
分子式：C22H17F2N5OS
分子量：437.47
EINECS号：
MDL No.：MFCD00941002
属性
熔点64-66°C
比旋光度D24 -29.1° (c = 1.03 in methanol)
沸点674.9±65.0 °C(Predicted)
密度1.38±0.1 g/cm3(Predicted)
储存条件-20°C Freezer
溶解度DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.25 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
酸度系数(pKa)11.62±0.29(Predicted)
形态A crystalline solid
颜色Off-white to yellow
旋光度 (Optical Rotation)[α]/D -27 to -33°, c =1 in methanol
InChIInChI=1S/C22H17F2N5OS/c1-14(21-28-20(10-31-21)16-4-2-15(9-25)3-5-16)22(30,11-29-13-26-12-27-29)18-7-6-17(23)8-19(18)24/h2-8,10,12-14,30H,11H2,1H3/t14-,22+/m0/s1
InChIKeyOPAHEYNNJWPQPX-RCDICMHDSA-N
SMILESC(#N)C1=CC=C(C2=CSC([C@H](C)[C@](C3=CC=C(F)C=C3F)(O)CN3C=NC=N3)=N2)C=C1